Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RB1	HGNC:9884 (HGNC) 5925 (Entrez Gene) 614041 (OMIM) RB1 (Alliance of Genome Resources)	Chr13 q14.2	Chr13:48303744-48599436 (+) GRCh38	familial retinoblastoma glioblastoma oligodendroglioma osteosarcoma prostate cancer retinoblastoma small cell carcinoma urinary bladder cancer	P06400 (UniProt | EBI) NM_001407168 (RefSeq)
mouse	Rb1	MGI:97874 (MGI) 19645 (Entrez Gene) Gene Tree Rb1 (Alliance of Genome Resources)	Chr14 38.73 cM	Chr14:73430298-73563446 (-) GRCm39		19645 (NCBI Gene Model) P13405 (UniProt | EBI) NM_009029 (RefSeq)
rat	Rb1	RGD:3540 (Rat Genome Database) 24708 (Entrez Gene) Rb1 (Alliance of Genome Resources)	Chr15 q11			P33568 (UniProt | EBI) NM_017045 (RefSeq)
zebrafish	rb1	ZDB-GENE-040428-1 (Zebrafish Model Organism Database) 777733 (Entrez Gene) rb1 (Alliance of Genome Resources)	Chr21			NP_001071248 (RefSeq) NM_001077780 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.