Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IMPA1	HGNC:6050 (HGNC) 3612 (Entrez Gene) 602064 (OMIM) IMPA1 (Alliance of Genome Resources)	Chr8 q21.13	Chr8:81656914-81686331 (-) GRCh38	autosomal recessive intellectual developmental disorder 59 intellectual disability	P29218 (UniProt | EBI) NM_001144878 (RefSeq)
mouse	Impa1	MGI:1933158 (MGI) 55980 (Entrez Gene) Gene Tree Impa1 (Alliance of Genome Resources)	Chr3 2.61 cM	Chr3:10377016-10396499 (-) GRCm39		55980 (NCBI Gene Model) O55023 (UniProt | EBI) NM_001428861 (RefSeq)
rat	Impa1	RGD:69254 (Rat Genome Database) 83523 (Entrez Gene) Impa1 (Alliance of Genome Resources)	Chr2 q23			P97697 (UniProt | EBI) NM_032057 (RefSeq)
zebrafish	impa1	ZDB-GENE-040718-245 (Zebrafish Model Organism Database) 437018 (Entrez Gene) impa1 (Alliance of Genome Resources)	Chr2			NP_001002745 (RefSeq) NM_001002745 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.