Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TYRP1	HGNC:12450 (HGNC) 7306 (Entrez Gene) 115501 (OMIM) TYRP1 (Alliance of Genome Resources)	Chr9 p23	Chr9:12685439-12710285 (+) GRCh38	oculocutaneous albinism oculocutaneous albinism type III pigmentation disease	P17643 (UniProt | EBI) NM_000550 (RefSeq)
mouse	Tyrp1	MGI:98881 (MGI) 22178 (Entrez Gene) Gene Tree Tyrp1 (Alliance of Genome Resources)	Chr4 37.89 cM	Chr4:80752360-80769956 (+) GRCm39		ENSMUSG00000005994 (Ensembl Gene Model) ENSMUSP00000099895 (Ensembl) ENSMUST00000102831 (Ensembl)
rat	Tyrp1	RGD:1593266 (Rat Genome Database) 298182 (Entrez Gene) Tyrp1 (Alliance of Genome Resources)	Chr5 q31			NP_001100134 (RefSeq) NM_001106664 (RefSeq)
zebrafish	tyrp1a	ZDB-GENE-070718-2 (Zebrafish Model Organism Database) 100333145 (Entrez Gene) tyrp1a (Alliance of Genome Resources)	Chr7			XP_021333754 (RefSeq)
	tyrp1b	ZDB-GENE-040718-249 (Zebrafish Model Organism Database) 437022 (Entrez Gene) tyrp1b (Alliance of Genome Resources)	Chr1			NP_001002749 (RefSeq) NM_001002749 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.