Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SREK1	HGNC:17882 (HGNC) 140890 (Entrez Gene) 609268 (OMIM) SREK1 (Alliance of Genome Resources)	Chr5 q12.3	Chr5:66139971-66183615 (+) GRCh38		Q8WXA9 (UniProt | EBI) NM_139168 (RefSeq)
mouse	Srek1	MGI:2145245 (MGI) 218543 (Entrez Gene) Gene Tree Srek1 (Alliance of Genome Resources)	Chr13 56.16 cM	Chr13:103875856-103911116 (-) GRCm39		ENSMUSG00000032621 (Ensembl Gene Model) ENSMUSP00000074196 (Ensembl) ENSMUST00000074616 (Ensembl)
rat	Srek1	RGD:621696 (Rat Genome Database) 56763 (Entrez Gene) Srek1 (Alliance of Genome Resources)	Chr2 q13			Q9JKL7 (UniProt | EBI) NM_020092 (RefSeq)
zebrafish	srek1	ZDB-GENE-040801-132 (Zebrafish Model Organism Database) 445219 (Entrez Gene) srek1 (Alliance of Genome Resources)	Chr5			NP_001003613 (RefSeq) NM_001003613 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.