Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PPP2R2B	HGNC:9305 (HGNC) 5521 (Entrez Gene) 604325 (OMIM) PPP2R2B (Alliance of Genome Resources)	Chr5 q32	Chr5:146580742-147084784 (-) GRCh38	Alzheimer's disease brain disease breast cancer spinocerebellar ataxia type 12	Q00005 (UniProt | EBI) NM_181677 (RefSeq)
mouse	Ppp2r2b	MGI:1920180 (MGI) 72930 (Entrez Gene) Gene Tree Ppp2r2b (Alliance of Genome Resources)	Chr18 22.75 cM	Chr18:42777811-43192827 (-) GRCm39		72930 (NCBI Gene Model) Q6ZWR4 (UniProt | EBI) NM_027531 (RefSeq)
rat	Ppp2r2b	RGD:631441 (Rat Genome Database) 60660 (Entrez Gene) Ppp2r2b (Alliance of Genome Resources)	Chr18 p11			P36877 (UniProt | EBI) NM_001402382 (RefSeq)
zebrafish	ppp2r2ba	ZDB-GENE-101026-5 (Zebrafish Model Organism Database) 100001644 (Entrez Gene) ppp2r2ba (Alliance of Genome Resources)	Chr14			XP_021336947 (RefSeq)
	ppp2r2bb	ZDB-GENE-041010-39 (Zebrafish Model Organism Database) 558810 (Entrez Gene) ppp2r2bb (Alliance of Genome Resources)	Chr21			NP_001025293 (RefSeq) NM_001030122 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.