Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	VPS53	HGNC:25608 (HGNC) 55275 (Entrez Gene) 615850 (OMIM) VPS53 (Alliance of Genome Resources)	Chr17 p13.3	Chr17:508503-721717 (-) GRCh38	pontocerebellar hypoplasia type 2E	Q5VIR6 (UniProt | EBI) NM_001366254 (RefSeq)
mouse	Vps53	MGI:1915549 (MGI) 68299 (Entrez Gene) Gene Tree Vps53 (Alliance of Genome Resources)	Chr11 45.92 cM	Chr11:75937052-76070464 (-) GRCm39		68299 (NCBI Gene Model) Q8CCB4 (UniProt | EBI) NM_026664 (RefSeq)
rat	Vps53	RGD:1311391 (Rat Genome Database) 287535 (Entrez Gene) Vps53 (Alliance of Genome Resources)	Chr10 q24			NP_001099283 (RefSeq) NM_001105813 (RefSeq)
zebrafish	vps53	ZDB-GENE-041114-199 (Zebrafish Model Organism Database) 492817 (Entrez Gene) vps53 (Alliance of Genome Resources)	Chr15			NP_001007459 (RefSeq) NM_001007458 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.