Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GUCA1A	HGNC:4678 (HGNC) 2978 (Entrez Gene) 600364 (OMIM) GUCA1A (Alliance of Genome Resources)	Chr6 p21.1	Chr6:42173364-42181338 (+) GRCh38	cone-rod dystrophy 14	P43080 (UniProt | EBI) NM_001384910 (RefSeq)
mouse	Guca1a	MGI:102770 (MGI) 14913 (Entrez Gene) Gene Tree Guca1a (Alliance of Genome Resources)	Chr17 23.07 cM	Chr17:47705483-47711509 (-) GRCm39		ENSMUSG00000023982 (Ensembl Gene Model) ENSMUSP00000060027 (Ensembl) ENSMUST00000059348 (Ensembl)
rat	Guca1a	RGD:1308712 (Rat Genome Database) 301233 (Entrez Gene) Guca1a (Alliance of Genome Resources)	Chr9 q12			NP_001100357 (RefSeq) NM_001106887 (RefSeq)
zebrafish	guca1aa	ZDB-GENE-011128-5 (Zebrafish Model Organism Database) 140430 (Entrez Gene) guca1aa (Alliance of Genome Resources)	Chr4			NP_571945 (RefSeq) NM_131870 (RefSeq)
	guca1ab.1	ZDB-GENE-040426-1577 (Zebrafish Model Organism Database) 393629 (Entrez Gene) guca1ab.1 (Alliance of Genome Resources)	Chr22			NP_956950 (RefSeq) NM_200656 (RefSeq)
	guca1ab.2	ZDB-GENE-091204-414 (Zebrafish Model Organism Database) 100330921 (Entrez Gene) guca1ab.2 (Alliance of Genome Resources)	Chr22			XP_002666176 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.