Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GJA1	HGNC:4274 (HGNC) 2697 (Entrez Gene) 121014 (OMIM) GJA1 (Alliance of Genome Resources)	Chr6 q22.31	Chr6:121435595-121449727 (+) GRCh38	autosomal recessive craniometaphyseal dysplasia erythrokeratodermia variabilis erythrokeratodermia variabilis et progressiva 3 hypoplastic left heart syndrome oculodentodigital dysplasia palmoplantar keratoderma and congenital alopecia 1 palmoplantar keratosis syndactyly type 3	P17302 (UniProt | EBI) NM_000165 (RefSeq)
mouse	Gja1	MGI:95713 (MGI) 14609 (Entrez Gene) Gene Tree Gja1 (Alliance of Genome Resources)	Chr10 28.64 cM	Chr10:56253297-56266519 (+) GRCm39	oculodentodigital dysplasia	14609 (NCBI Gene Model) P23242 (UniProt | EBI) NM_001428500 (RefSeq)
rat	Gja1	RGD:2690 (Rat Genome Database) 24392 (Entrez Gene) Gja1 (Alliance of Genome Resources)	Chr20 q11			P08050 (UniProt | EBI) NM_001429428 (RefSeq)
zebrafish	gja1a	ZDB-GENE-050616-10 (Zebrafish Model Organism Database) 565638 (Entrez Gene) gja1a (Alliance of Genome Resources)	Chr17			XP_693998 (RefSeq)
	gja1b	ZDB-GENE-991105-4 (Zebrafish Model Organism Database) 30236 (Entrez Gene) gja1b (Alliance of Genome Resources)	Chr20			O57474 (UniProt | EBI) NM_131038 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.