Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PTS	HGNC:9689 (HGNC) 5805 (Entrez Gene) 612719 (OMIM) PTS (Alliance of Genome Resources)	Chr11 q23.1	Chr11:112226367-112269955 (+) GRCh38	BH4-deficient hyperphenylalaninemia A phenylketonuria	Q03393 (UniProt | EBI) NM_000317 (RefSeq)
mouse	Pts	MGI:1338783 (MGI) 19286 (Entrez Gene) Gene Tree Pts (Alliance of Genome Resources)	Chr9 27.73 cM	Chr9:50432917-50440017 (-) GRCm39	BH4-deficient hyperphenylalaninemia A	19286 (NCBI Gene Model) Q9R1Z7 (UniProt | EBI) NM_001409198 (RefSeq)
rat	Pts	RGD:68367 (Rat Genome Database) 29498 (Entrez Gene) Pts (Alliance of Genome Resources)	Chr8 q23			P27213 (UniProt | EBI) NM_001409516 (RefSeq)
zebrafish	pts	ZDB-GENE-070615-3 (Zebrafish Model Organism Database) 100073330 (Entrez Gene) pts (Alliance of Genome Resources)	Chr12			NP_001092237 (RefSeq) NM_001098767 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.