Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DIS3L2	HGNC:28648 (HGNC) 129563 (Entrez Gene) 614184 (OMIM) DIS3L2 (Alliance of Genome Resources)	Chr2 q37.1	Chr2:231961245-232344350 (+) GRCh38	nephroblastoma Perlman syndrome	Q8IYB7 (UniProt | EBI) NM_152383 (RefSeq)
mouse	Dis3l2	MGI:2442555 (MGI) 208718 (Entrez Gene) Gene Tree Dis3l2 (Alliance of Genome Resources)	Chr1 43.99 cM	Chr1:86631530-86977817 (+) GRCm39	Perlman syndrome	ENSMUSG00000053333 (Ensembl Gene Model) ENSMUSP00000132673 (Ensembl) ENSMUST00000168237 (Ensembl)
rat	Dis3l2	RGD:1560168 (Rat Genome Database) 367307 (Entrez Gene) Dis3l2 (Alliance of Genome Resources)	Chr9 q35			NP_001102477 (RefSeq) NM_001172159 (RefSeq)
zebrafish	dis3l2	ZDB-GENE-070705-171 (Zebrafish Model Organism Database) 566106 (Entrez Gene) dis3l2 (Alliance of Genome Resources)	Chr2			XP_005163305 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.