Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RIT1	HGNC:10023 (HGNC) 6016 (Entrez Gene) 609591 (OMIM) RIT1 (Alliance of Genome Resources)	Chr1 q22	Chr1:155897808-155911404 (-) GRCh38	hepatocellular carcinoma Noonan syndrome Noonan syndrome 8 RASopathy	Q92963 (UniProt | EBI) NM_001256820 (RefSeq)
mouse	Rit1	MGI:108053 (MGI) 19769 (Entrez Gene) Gene Tree Rit1 (Alliance of Genome Resources)	Chr3 38.95 cM	Chr3:88624154-88638354 (+) GRCm39	Noonan syndrome 8	19769 (NCBI Gene Model) P70426 (UniProt | EBI) NM_001404036 (RefSeq)
rat	Rit1	RGD:1559874 (Rat Genome Database) 499652 (Entrez Gene) Rit1 (Alliance of Genome Resources)	Chr2 q34			NP_001383471 (RefSeq) NM_001396541 (RefSeq)
zebrafish	rit1	ZDB-GENE-070912-329 (Zebrafish Model Organism Database) 793942 (Entrez Gene) rit1 (Alliance of Genome Resources)	Chr19			NP_001122253 (RefSeq) NM_001128781 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.