Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ACTA1	HGNC:129 (HGNC) 58 (Entrez Gene) 102610 (OMIM) ACTA1 (Alliance of Genome Resources)	Chr1 q42.13	Chr1:229430365-229434104 (-) GRCh38	congenital myopathy 2B congenital myopathy 2C nemaline myopathy 3	P68133 (UniProt | EBI) NM_001100 (RefSeq)
mouse	Acta1	MGI:87902 (MGI) 11459 (Entrez Gene) Gene Tree Acta1 (Alliance of Genome Resources)	Chr8 72.26 cM	Chr8:124618508-124621490 (-) GRCm39	nemaline myopathy 3	ENSMUSG00000031972 (Ensembl Gene Model) ENSMUSP00000034453 (Ensembl) ENSMUST00000034453 (Ensembl)
rat	Acta1	RGD:2025 (Rat Genome Database) 29437 (Entrez Gene) Acta1 (Alliance of Genome Resources)	Chr19 q12			P68136 (UniProt | EBI) NM_019212 (RefSeq)
zebrafish	acta1a	ZDB-GENE-050417-267 (Zebrafish Model Organism Database) 550445 (Entrez Gene) acta1a (Alliance of Genome Resources)	Chr1			NP_001017750 (RefSeq) NM_001017750 (RefSeq)
	acta1b	ZDB-GENE-030131-55 (Zebrafish Model Organism Database) 407658 (Entrez Gene) acta1b (Alliance of Genome Resources)	Chr13			NP_999949 (RefSeq) NM_214784 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.