Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PI4KA	HGNC:8983 (HGNC) 5297 (Entrez Gene) 600286 (OMIM) PI4KA (Alliance of Genome Resources)	Chr22 q11.21	Chr22:20707691-20859417 (-) GRCh38	hereditary spastic paraplegia 84	P42356 (UniProt | EBI) NM_002650 (RefSeq)
mouse	Pi4ka	MGI:2448506 (MGI) 224020 (Entrez Gene) Gene Tree Pi4ka (Alliance of Genome Resources)	Chr16 10.71 cM	Chr16:17098215-17224178 (-) GRCm39		224020 (NCBI Gene Model) E9Q3L2 (UniProt | EBI) NM_001373955 (RefSeq)
rat	Pi4ka	RGD:621213 (Rat Genome Database) 64161 (Entrez Gene) Pi4ka (Alliance of Genome Resources)	Chr11 q23			O08662 (UniProt | EBI) NM_001415014 (RefSeq)
zebrafish	pi4kaa	ZDB-GENE-100204-2 (Zebrafish Model Organism Database) 556956 (Entrez Gene) pi4kaa (Alliance of Genome Resources)	Chr10			NP_001030144 (RefSeq) NM_001034972 (RefSeq)
	pi4kab	ZDB-GENE-080220-34 (Zebrafish Model Organism Database) 793349 (Entrez Gene) pi4kab (Alliance of Genome Resources)	Chr8			NP_001106813 (RefSeq) NM_001113342 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.