Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HSPG2	HGNC:5273 (HGNC) 3339 (Entrez Gene) 142461 (OMIM) HSPG2 (Alliance of Genome Resources)	Chr1 p36.12	Chr1:21822244-21937310 (-) GRCh38	osteochondrodysplasia Schwartz-Jampel syndrome 1 Silverman-Handmaker type dyssegmental dysplasia	P98160 (UniProt | EBI) NM_001291860 (RefSeq)
mouse	Hspg2	MGI:96257 (MGI) 15530 (Entrez Gene) Gene Tree Hspg2 (Alliance of Genome Resources)	Chr4 69.93 cM	Chr4:137196080-137297941 (+) GRCm39	dextro-looped transposition of the great arteries Schwartz-Jampel syndrome 1 Silverman-Handmaker type dyssegmental dysplasia thanatophoric dysplasia	ENSMUSG00000028763 (Ensembl Gene Model) ENSMUSP00000131316 (Ensembl) ENSMUST00000171332 (Ensembl)
rat	Hspg2	RGD:621770 (Rat Genome Database) 313641 (Entrez Gene) Hspg2 (Alliance of Genome Resources)	Chr5 q36			NP_001414367 (RefSeq) NM_001427438 (RefSeq)
zebrafish	hspg2	ZDB-GENE-080807-4 (Zebrafish Model Organism Database) 565429 (Entrez Gene) hspg2 (Alliance of Genome Resources)	Chr23			XP_021325657 (RefSeq) NM_001127467 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.