Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ALOX5	HGNC:435 (HGNC) 240 (Entrez Gene) 152390 (OMIM) ALOX5 (Alliance of Genome Resources)	Chr10 q11.21	Chr10:45374176-45446119 (+) GRCh38	arteriosclerosis asthma exercise-induced bronchoconstriction pancreatic cancer pulmonary hypertension pulmonary tuberculosis	P09917 (UniProt | EBI) NM_001256154 (RefSeq)
mouse	Alox5	MGI:87999 (MGI) 11689 (Entrez Gene) Gene Tree Alox5 (Alliance of Genome Resources)	Chr6 53.79 cM	Chr6:116387038-116438139 (-) GRCm39		ENSMUSG00000025701 (Ensembl Gene Model) ENSMUSP00000026795 (Ensembl) ENSMUST00000026795 (Ensembl)
rat	Alox5	RGD:2096 (Rat Genome Database) 25290 (Entrez Gene) Alox5 (Alliance of Genome Resources)	Chr4 q42			P12527 (UniProt | EBI) NM_012822 (RefSeq)
zebrafish	alox5a	ZDB-GENE-090311-47 (Zebrafish Model Organism Database) 567204 (Entrez Gene) alox5a (Alliance of Genome Resources)	Chr13			NP_001290191 (RefSeq) NM_001256747 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.