Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDE6B	HGNC:8786 (HGNC) 5158 (Entrez Gene) 180072 (OMIM) PDE6B (Alliance of Genome Resources)	Chr4 p16.3	Chr4:625573-670782 (+) GRCh38	congenital stationary night blindness autosomal dominant 2 retinitis pigmentosa 40	P35913 (UniProt | EBI) NM_000283 (RefSeq)
mouse	Pde6b	MGI:97525 (MGI) 18587 (Entrez Gene) Gene Tree Pde6b (Alliance of Genome Resources)	Chr5 53.07 cM	Chr5:108536239-108579609 (+) GRCm39	congenital stationary night blindness autosomal dominant 2 retinal degeneration retinitis pigmentosa retinitis pigmentosa 40	18587 (NCBI Gene Model) P23440 (UniProt | EBI) NM_008806 (RefSeq)
rat	Pde6b	RGD:1311039 (Rat Genome Database) 289878 (Entrez Gene) Pde6b (Alliance of Genome Resources)	Chr14 p22			NP_001099494 (RefSeq) NM_001106024 (RefSeq)
zebrafish	pde6b	ZDB-GENE-090421-2 (Zebrafish Model Organism Database) 559332 (Entrez Gene) pde6b (Alliance of Genome Resources)	Chr21			XP_685002 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.