Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	JUP	HGNC:6207 (HGNC) 3728 (Entrez Gene) 173325 (OMIM) JUP (Alliance of Genome Resources)	Chr17 q21.2	Chr17:41754604-41786931 (-) GRCh38	arrhythmogenic right ventricular dysplasia 12 cardiomyopathy Naxos disease ovarian cancer palmoplantar keratosis prostate cancer renal cell carcinoma	P14923 (UniProt | EBI) NM_001352774 (RefSeq)
mouse	Jup	MGI:96650 (MGI) 16480 (Entrez Gene) Gene Tree Jup (Alliance of Genome Resources)	Chr11 63.47 cM	Chr11:100259784-100288589 (-) GRCm39	arrhythmogenic right ventricular dysplasia 12 epidermolytic hyperkeratosis	ENSMUSG00000001552 (Ensembl Gene Model) ENSMUSP00000103026 (Ensembl) ENSMUST00000107403 (Ensembl)
rat	Jup	RGD:620412 (Rat Genome Database) 81679 (Entrez Gene) Jup (Alliance of Genome Resources)	Chr10 q31			Q6P0K8 (UniProt | EBI) NM_031047 (RefSeq)
zebrafish	jupa	ZDB-GENE-991207-22 (Zebrafish Model Organism Database) 30415 (Entrez Gene) jupa (Alliance of Genome Resources)	Chr11			NP_571252 (RefSeq) NM_131177 (RefSeq)
	jupb	ZDB-GENE-110407-10 (Zebrafish Model Organism Database) 100330886 (Entrez Gene) jupb (Alliance of Genome Resources)	Chr19			XP_021323940 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.