Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DBH	HGNC:2689 (HGNC) 1621 (Entrez Gene) 609312 (OMIM) DBH (Alliance of Genome Resources)	Chr9 q34.2	Chr9:133636363-133659329 (+) GRCh38	alcohol use disorder attention deficit hyperactivity disorder dopamine beta-hydroxylase deficiency hypertension migraine with aura Parkinson's disease	P09172 (UniProt | EBI) NM_000787 (RefSeq)
mouse	Dbh	MGI:94864 (MGI) 13166 (Entrez Gene) Gene Tree Dbh (Alliance of Genome Resources)	Chr2 19.29 cM	Chr2:27055519-27073216 (+) GRCm39	dopamine beta-hydroxylase deficiency	13166 (NCBI Gene Model) Q64237 (UniProt | EBI) NM_138942 (RefSeq)
rat	Dbh	RGD:2489 (Rat Genome Database) 25699 (Entrez Gene) Dbh (Alliance of Genome Resources)	Chr3 p12			Q05754 (UniProt | EBI) NM_013158 (RefSeq)
zebrafish	dbh	ZDB-GENE-990621-3 (Zebrafish Model Organism Database) 30505 (Entrez Gene) dbh (Alliance of Genome Resources)	Chr10			NP_001103164 (RefSeq) NM_001109694 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.