Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ALPL	HGNC:438 (HGNC) 249 (Entrez Gene) 171760 (OMIM) ALPL (Alliance of Genome Resources)	Chr1 p36.12	Chr1:21508984-21578410 (+) GRCh38	adult hypophosphatasia childhood hypophosphatasia hypophosphatasia infantile hypophosphatasia	P05186 (UniProt | EBI) NM_001369804 (RefSeq)
mouse	Alpl	MGI:87983 (MGI) 11647 (Entrez Gene) Gene Tree Alpl (Alliance of Genome Resources)	Chr4 70.02 cM	Chr4:137469044-137523695 (-) GRCm39	adult hypophosphatasia childhood hypophosphatasia infantile hypophosphatasia	ENSMUSG00000028766 (Ensembl Gene Model) ENSMUSP00000030551 (Ensembl) ENSMUST00000030551 (Ensembl)
rat	Alpl	RGD:2100 (Rat Genome Database) 25586 (Entrez Gene) Alpl (Alliance of Genome Resources)	Chr5 q36			P08289 (UniProt | EBI) NM_001429380 (RefSeq)
zebrafish	alpl	ZDB-GENE-040420-1 (Zebrafish Model Organism Database) 393982 (Entrez Gene) alpl (Alliance of Genome Resources)	Chr11			NP_957301 (RefSeq) NM_201007 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.