Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPTA1	HGNC:11272 (HGNC) 6708 (Entrez Gene) 182860 (OMIM) SPTA1 (Alliance of Genome Resources)	Chr1 q23.1	Chr1:158610704-158686715 (-) GRCh38	hereditary spherocytosis hereditary spherocytosis type 3	P02549 (UniProt | EBI) NM_003126 (RefSeq)
mouse	Spta1	MGI:98385 (MGI) 20739 (Entrez Gene) Gene Tree Spta1 (Alliance of Genome Resources)	Chr1 80.97 cM	Chr1:174000342-174076016 (+) GRCm39	hereditary spherocytosis type 1 hereditary spherocytosis type 3 sickle cell anemia	ENSMUSG00000026532 (Ensembl Gene Model) ENSMUSP00000027817 (Ensembl) ENSMUST00000027817 (Ensembl)
rat	Spta1	RGD:1305194 (Rat Genome Database) 289257 (Entrez Gene) Spta1 (Alliance of Genome Resources)	Chr13 q24			NP_001011908 (RefSeq) NM_001011908 (RefSeq)
zebrafish	sptbn4a	ZDB-GENE-060531-133 (Zebrafish Model Organism Database) 100003123 (Entrez Gene) sptbn4a (Alliance of Genome Resources)	Chr5			XP_001342754 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.