Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SRSF2	HGNC:10783 (HGNC) 6427 (Entrez Gene) 600813 (OMIM) SRSF2 (Alliance of Genome Resources)	Chr17 q25.1	Chr17:76734115-76737411 (-) GRCh38	acute myeloid leukemia congestive heart failure hepatocellular carcinoma myelodysplastic syndrome	Q01130 (UniProt | EBI) NM_001195427 (RefSeq)
mouse	Srsf2	MGI:98284 (MGI) 20382 (Entrez Gene) Gene Tree Srsf2 (Alliance of Genome Resources)	Chr11 81.49 cM	Chr11:116740727-116743920 (-) GRCm39	myelodysplastic syndrome	ENSMUSG00000034120 (Ensembl Gene Model) ENSMUSP00000090059 (Ensembl) ENSMUST00000092404 (Ensembl)
rat	Srsf2	RGD:1359422 (Rat Genome Database) 494445 (Entrez Gene) Srsf2 (Alliance of Genome Resources)	Chr10 q32.2			Q6PDU1 (UniProt | EBI) NM_001009720 (RefSeq)
zebrafish	srsf2a	ZDB-GENE-040426-2706 (Zebrafish Model Organism Database) 406691 (Entrez Gene) srsf2a (Alliance of Genome Resources)	Chr12			NP_998547 (RefSeq) NM_213382 (RefSeq)
	srsf2b	ZDB-GENE-030131-2420 (Zebrafish Model Organism Database) 323700 (Entrez Gene) srsf2b (Alliance of Genome Resources)	Chr3			NP_955945 (RefSeq) NM_199651 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.