Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TBL1XR1	HGNC:29529 (HGNC) 79718 (Entrez Gene) 608628 (OMIM) TBL1XR1 (Alliance of Genome Resources)	Chr3 q26.32	Chr3:177019340-177228000 (-) GRCh38	autosomal dominant intellectual developmental disorder 41 Pierpont syndrome	Q9BZK7 (UniProt | EBI) NM_001321195 (RefSeq)
mouse	Tbl1xr1	MGI:2441730 (MGI) 81004 (Entrez Gene) Gene Tree Tbl1xr1 (Alliance of Genome Resources)	Chr3 7.58 cM	Chr3:22130816-22270758 (+) GRCm39	Pierpont syndrome	ENSMUSG00000027630 (Ensembl Gene Model) ENSMUSP00000142184 (Ensembl) ENSMUST00000193734 (Ensembl)
rat	Tbl1xr1	RGD:1560053 (Rat Genome Database) 365755 (Entrez Gene) Tbl1xr1 (Alliance of Genome Resources)	Chr2 q24			NP_001102411 (RefSeq) NM_001108941 (RefSeq)
zebrafish	tbl1xr1a	ZDB-GENE-050522-314 (Zebrafish Model Organism Database) 553608 (Entrez Gene) tbl1xr1a (Alliance of Genome Resources)	Chr11			NP_001018419 (RefSeq) NM_001020583 (RefSeq)
	tbl1xr1b	ZDB-GENE-040426-1192 (Zebrafish Model Organism Database) 393581 (Entrez Gene) tbl1xr1b (Alliance of Genome Resources)	Chr2			NP_001313469 (RefSeq) NM_200609 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.