Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NOTCH4	HGNC:7884 (HGNC) 4855 (Entrez Gene) 164951 (OMIM) NOTCH4 (Alliance of Genome Resources)	Chr6 p21.32	Chr6:32194843-32224067 (-) GRCh38	alopecia areata dementia ductal carcinoma in situ multiple sclerosis schizophrenia systemic scleroderma type 1 diabetes mellitus	Q99466 (UniProt | EBI) NM_004557 (RefSeq)
mouse	Notch4	MGI:107471 (MGI) 18132 (Entrez Gene) Gene Tree Notch4 (Alliance of Genome Resources)	Chr17 18.15 cM	Chr17:34783242-34807477 (+) GRCm39	arteriovenous malformations of the brain	ENSMUSG00000015468 (Ensembl Gene Model) ENSMUSP00000015612 (Ensembl) ENSMUST00000015612 (Ensembl)
rat	Notch4	RGD:1303282 (Rat Genome Database) 406162 (Entrez Gene) Notch4 (Alliance of Genome Resources)	Chr20 p12			NP_001002827 (RefSeq) NM_001002827 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.