Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CAT	HGNC:1516 (HGNC) 847 (Entrez Gene) 115500 (OMIM) CAT (Alliance of Genome Resources)	Chr11 p13	Chr11:34438934-34472060 (+) GRCh38	acatalasia angle-closure glaucoma asthma essential hypertension hepatocellular carcinoma keratosis lung disease melanoma newborn respiratory distress syndrome optic neuritis osteonecrosis pseudoxanthoma elasticum retinitis pigmentosa senile cataract vitiligo	P04040 (UniProt | EBI) NM_001752 (RefSeq)
mouse	Cat	MGI:88271 (MGI) 12359 (Entrez Gene) Gene Tree Cat (Alliance of Genome Resources)	Chr2 54.43 cM	Chr2:103284249-103315498 (-) GRCm39		12359 (NCBI Gene Model) P24270 (UniProt | EBI) NM_009804 (RefSeq)
rat	Cat	RGD:2279 (Rat Genome Database) 24248 (Entrez Gene) Cat (Alliance of Genome Resources)	Chr3 q32			P04762 (UniProt | EBI) NM_012520 (RefSeq)
zebrafish	cat	ZDB-GENE-000210-20 (Zebrafish Model Organism Database) 30068 (Entrez Gene) cat (Alliance of Genome Resources)	Chr25			Q9PT92 (UniProt | EBI) NM_130912 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.