Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AGXT	HGNC:341 (HGNC) 189 (Entrez Gene) 604285 (OMIM) AGXT (Alliance of Genome Resources)	Chr2 q37.3	Chr2:240868824-240880502 (+) GRCh38	primary hyperoxaluria type 1	P21549 (UniProt | EBI) NM_000030 (RefSeq)
mouse	Agxt	MGI:1329033 (MGI) 11611 (Entrez Gene) Gene Tree Agxt (Alliance of Genome Resources)	Chr1 47.0 cM	Chr1:93062962-93073143 (+) GRCm39	primary hyperoxaluria type 1	11611 (NCBI Gene Model) O35423 (UniProt | EBI) NM_001276710 (RefSeq)
rat	Agxt	RGD:2073 (Rat Genome Database) 24792 (Entrez Gene) Agxt (Alliance of Genome Resources)	Chr9 q36			P09139 (UniProt | EBI) NM_001276706 (RefSeq)
zebrafish	agxta	ZDB-GENE-040718-16 (Zebrafish Model Organism Database) 436603 (Entrez Gene) agxta (Alliance of Genome Resources)	Chr6			NP_001002331 (RefSeq) NM_001002331 (RefSeq)
	agxtb	ZDB-GENE-010302-3 (Zebrafish Model Organism Database) 79378 (Entrez Gene) agxtb (Alliance of Genome Resources)	Chr2			NP_998327 (RefSeq) NM_213162 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.