Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PBRM1	HGNC:30064 (HGNC) 55193 (Entrez Gene) 606083 (OMIM) PBRM1 (Alliance of Genome Resources)	Chr3 p21.1	Chr3:52545352-52685917 (-) GRCh38	extrahepatic bile duct adenocarcinoma lung non-small cell carcinoma lung small cell carcinoma renal cell carcinoma	Q86U86 (UniProt | EBI) NM_001405613 (RefSeq)
mouse	Pbrm1	MGI:1923998 (MGI) 66923 (Entrez Gene) Gene Tree Pbrm1 (Alliance of Genome Resources)	Chr14 19.09 cM	Chr14:30741095-30843549 (+) GRCm39		66923 (NCBI Gene Model) Q8BSQ9 (UniProt | EBI) NM_001359854 (RefSeq)
rat	Pbrm1	RGD:1565549 (Rat Genome Database) 306254 (Entrez Gene) Pbrm1 (Alliance of Genome Resources)	Chr16 p16			NP_001414614 (RefSeq) NM_001427685 (RefSeq)
zebrafish	pbrm1	ZDB-GENE-080926-4 (Zebrafish Model Organism Database) 565366 (Entrez Gene) pbrm1 (Alliance of Genome Resources)	Chr11			XP_009304062 (RefSeq)
	pbrm1l	ZDB-GENE-010501-3 (Zebrafish Model Organism Database) 445141 (Entrez Gene) pbrm1l (Alliance of Genome Resources)	Chr6			NP_001003535 (RefSeq) NM_001003535 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.