Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GUCY2D	HGNC:4689 (HGNC) 3000 (Entrez Gene) 600179 (OMIM) GUCY2D (Alliance of Genome Resources)	Chr17 p13.1	Chr17:8002615-8020342 (+) GRCh38	choroidal sclerosis cone-rod dystrophy 6 congenital stationary night blindness Leber congenital amaurosis 1 retinitis pigmentosa	Q02846 (UniProt | EBI) NM_000180 (RefSeq)
mouse	Gucy2e	MGI:105123 (MGI) 14919 (Entrez Gene) Gene Tree Gucy2e (Alliance of Genome Resources)	Chr11 42.51 cM	Chr11:69108943-69127862 (-) GRCm39	cone-rod dystrophy 6 Leber congenital amaurosis 1	ENSMUSG00000020890 (Ensembl Gene Model) ENSMUSP00000021259 (Ensembl) ENSMUST00000021259 (Ensembl)
rat	Gucy2d	RGD:620438 (Rat Genome Database) 79222 (Entrez Gene) Gucy2d (Alliance of Genome Resources)	Chr10 q24			P51840 (UniProt | EBI) NM_024380 (RefSeq)
zebrafish	gucy2d	ZDB-GENE-011128-9 (Zebrafish Model Organism Database) 140426 (Entrez Gene) gucy2d (Alliance of Genome Resources)	Chr5			NP_571941 (RefSeq) NM_131866 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.