Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	JAG2	HGNC:6189 (HGNC) 3714 (Entrez Gene) 602570 (OMIM) JAG2 (Alliance of Genome Resources)	Chr14 q32.33	Chr14:105140982-105168824 (-) GRCh38	autosomal recessive limb-girdle muscular dystrophy	Q9Y219 (UniProt | EBI) NM_145159 (RefSeq)
mouse	Jag2	MGI:1098270 (MGI) 16450 (Entrez Gene) Gene Tree Jag2 (Alliance of Genome Resources)	Chr12 61.37 cM	Chr12:112871439-112893396 (-) GRCm39		ENSMUSG00000002799 (Ensembl Gene Model) ENSMUSP00000075224 (Ensembl) ENSMUST00000075827 (Ensembl)
rat	Jag2	RGD:2938 (Rat Genome Database) 29147 (Entrez Gene) Jag2 (Alliance of Genome Resources)	Chr6 q32			P97607 (UniProt | EBI) NM_001414899 (RefSeq)
zebrafish	jag2a	ZDB-GENE-130530-549 (Zebrafish Model Organism Database) 566455 (Entrez Gene) jag2a (Alliance of Genome Resources)	Chr13			XP_005157022 (RefSeq)
	jag2b	ZDB-GENE-011128-3 (Zebrafish Model Organism Database) 140422 (Entrez Gene) jag2b (Alliance of Genome Resources)	Chr20			NP_571937 (RefSeq) NM_131862 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.