Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MYO7A	HGNC:7606 (HGNC) 4647 (Entrez Gene) 276903 (OMIM) MYO7A (Alliance of Genome Resources)	Chr11 q13.5	Chr11:77128246-77215241 (+) GRCh38	autosomal dominant nonsyndromic deafness 11 autosomal recessive nonsyndromic deafness 2 congenital nystagmus Leber congenital amaurosis sensorineural hearing loss Usher syndrome Usher syndrome type 1	Q13402 (UniProt | EBI) NM_000260 (RefSeq)
mouse	Myo7a	MGI:104510 (MGI) 17921 (Entrez Gene) Gene Tree Myo7a (Alliance of Genome Resources)	Chr7 53.57 cM	Chr7:97700267-97768731 (-) GRCm39	autosomal recessive nonsyndromic deafness 2 Usher syndrome type 1	ENSMUSG00000030761 (Ensembl Gene Model) ENSMUSP00000102745 (Ensembl) ENSMUST00000107128 (Ensembl)
rat	Myo7a	RGD:628830 (Rat Genome Database) 266714 (Entrez Gene) Myo7a (Alliance of Genome Resources)	Chr1 q32			NP_001401672 (RefSeq) NM_153473 (RefSeq)
zebrafish	myo7aa	ZDB-GENE-020709-1 (Zebrafish Model Organism Database) 252846 (Entrez Gene) myo7aa (Alliance of Genome Resources)	Chr18			NP_694515 (RefSeq) NM_152983 (RefSeq)
	myo7ab	ZDB-GENE-091110-4 (Zebrafish Model Organism Database) 556141 (Entrez Gene) myo7ab (Alliance of Genome Resources)	Chr21			XP_009293671 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.