Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HDAC6	HGNC:14064 (HGNC) 10013 (Entrez Gene) 300272 (OMIM) HDAC6 (Alliance of Genome Resources)	ChrX p11.23	ChrX:48801377-48824982 (+) GRCh38	chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia	Q9UBN7 (UniProt | EBI) NM_001321231 (RefSeq)
mouse	Hdac6	MGI:1333752 (MGI) 15185 (Entrez Gene) Gene Tree Hdac6 (Alliance of Genome Resources)	ChrX 3.58 cM	ChrX:7796359-7814128 (-) GRCm39		ENSMUSG00000031161 (Ensembl Gene Model) ENSMUSP00000111306 (Ensembl) ENSMUST00000115642 (Ensembl)
zebrafish	hdac6	ZDB-GENE-030131-3232 (Zebrafish Model Organism Database) 565482 (Entrez Gene) hdac6 (Alliance of Genome Resources)	Chr8			XP_009302026 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.