Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MMP13	HGNC:7159 (HGNC) 4322 (Entrez Gene) 600108 (OMIM) MMP13 (Alliance of Genome Resources)	Chr11 q22.2	Chr11:102942995-102955732 (-) GRCh38	abdominal aortic aneurysm anodontia arteriosclerosis osteoarthritis ovarian carcinoma spondyloepimetaphyseal dysplasia, Missouri type	P45452 (UniProt | EBI) NM_002427 (RefSeq)
mouse	Mmp13	MGI:1340026 (MGI) 17386 (Entrez Gene) Gene Tree Mmp13 (Alliance of Genome Resources)	Chr9 2.46 cM	Chr9:7272514-7283331 (+) GRCm39		ENSMUSG00000050578 (Ensembl Gene Model) ENSMUSP00000015394 (Ensembl) ENSMUST00000015394 (Ensembl)
rat	Mmp13	RGD:620196 (Rat Genome Database) 171052 (Entrez Gene) Mmp13 (Alliance of Genome Resources)	Chr8 q11			P23097 (UniProt | EBI) NM_133530 (RefSeq)
zebrafish	mmp13a	ZDB-GENE-031202-2 (Zebrafish Model Organism Database) 387293 (Entrez Gene) mmp13a (Alliance of Genome Resources)	Chr10			NP_001277408 (RefSeq) NM_001290479 (RefSeq)
	mmp13b	ZDB-GENE-030131-6152 (Zebrafish Model Organism Database) 100006896 (Entrez Gene) mmp13b (Alliance of Genome Resources)	Chr15			XP_001345507 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.