Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MARK3	HGNC:6897 (HGNC) 4140 (Entrez Gene) 602678 (OMIM) MARK3 (Alliance of Genome Resources)	Chr14 q32.32-q32.33	Chr14:103385377-103503831 (+) GRCh38	visual impairment and progressive phthisis bulbi	P27448 (UniProt | EBI) NM_001128918 (RefSeq)
mouse	Mark3	MGI:1341865 (MGI) 17169 (Entrez Gene) Gene Tree Mark3 (Alliance of Genome Resources)	Chr12 61.05 cM	Chr12:111540957-111622655 (+) GRCm39		ENSMUSG00000007411 (Ensembl Gene Model) ENSMUSP00000152727 (Ensembl) ENSMUST00000221753 (Ensembl)
rat	Mark3	RGD:619883 (Rat Genome Database) 170577 (Entrez Gene) Mark3 (Alliance of Genome Resources)	Chr6 q32			Q8VHF0 (UniProt | EBI) NM_130749 (RefSeq)
zebrafish	mark3a	ZDB-GENE-030131-6232 (Zebrafish Model Organism Database) 334300 (Entrez Gene) mark3a (Alliance of Genome Resources)	Chr13			NP_956179 (RefSeq) NM_001077459 (RefSeq)
	mark3b	ZDB-GENE-060929-80 (Zebrafish Model Organism Database) 767634 (Entrez Gene) mark3b (Alliance of Genome Resources)	Chr20			NP_001070043 (RefSeq) NM_001076575 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.