Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PHGDH	HGNC:8923 (HGNC) 26227 (Entrez Gene) 606879 (OMIM) PHGDH (Alliance of Genome Resources)	Chr1 p12	Chr1:119648411-119744218 (+) GRCh38	amino acid metabolic disorder Neu-Laxova syndrome 1 PHGDH deficiency	O43175 (UniProt | EBI) NM_006623 (RefSeq)
mouse	Phgdh	MGI:1355330 (MGI) 236539 (Entrez Gene) Gene Tree Phgdh (Alliance of Genome Resources)	Chr3 42.74 cM	Chr3:98220487-98247285 (-) GRCm39		236539 (NCBI Gene Model) Q61753 (UniProt | EBI) NM_016966 (RefSeq)
rat	Phgdh	RGD:61987 (Rat Genome Database) 58835 (Entrez Gene) Phgdh (Alliance of Genome Resources)	Chr2 q34			O08651 (UniProt | EBI) NM_031620 (RefSeq)
zebrafish	phgdh	ZDB-GENE-030131-647 (Zebrafish Model Organism Database) 321928 (Entrez Gene) phgdh (Alliance of Genome Resources)	Chr9			NP_955871 (RefSeq) NM_199577 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.