Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MDH1	HGNC:6970 (HGNC) 4190 (Entrez Gene) 154200 (OMIM) MDH1 (Alliance of Genome Resources)	Chr2 p15	Chr2:63588609-63607197 (+) GRCh38	developmental and epileptic encephalopathy 88	P40925 (UniProt | EBI) NM_001199111 (RefSeq)
mouse	Mdh1	MGI:97051 (MGI) 17449 (Entrez Gene) Gene Tree Mdh1 (Alliance of Genome Resources)	Chr11 13.89 cM	Chr11:21506692-21521934 (-) GRCm39		17449 (NCBI Gene Model) P14152 (UniProt | EBI) NM_001316675 (RefSeq)
rat	Mdh1	RGD:3072 (Rat Genome Database) 24551 (Entrez Gene) Mdh1 (Alliance of Genome Resources)	Chr14 q22			O88989 (UniProt | EBI) NM_033235 (RefSeq)
zebrafish	mdh1aa	ZDB-GENE-040204-1 (Zebrafish Model Organism Database) 399662 (Entrez Gene) mdh1aa (Alliance of Genome Resources)	Chr1			NP_001296452 (RefSeq) NM_001316925 (RefSeq)
	mdh1ab	ZDB-GENE-030131-7655 (Zebrafish Model Organism Database) 335715 (Entrez Gene) mdh1ab (Alliance of Genome Resources)	Chr17			NP_001342482 (RefSeq) NM_001355543 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.