Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SDHB	HGNC:10681 (HGNC) 6390 (Entrez Gene) 185470 (OMIM) SDHB (Alliance of Genome Resources)	Chr1 p36.13	Chr1:17018664-17054151 (-) GRCh38	Carney-Stratakis syndrome gastrointestinal stromal tumor mitochondrial complex II deficiency paraganglioma pheochromocytoma	P21912 (UniProt | EBI) NM_003000 (RefSeq)
mouse	Sdhb	MGI:1914930 (MGI) 67680 (Entrez Gene) Gene Tree Sdhb (Alliance of Genome Resources)	Chr4 73.24 cM	Chr4:140688582-140706509 (+) GRCm39	type 2 diabetes mellitus	67680 (NCBI Gene Model) Q9CQA3 (UniProt | EBI) NM_023374 (RefSeq)
rat	Sdhb	RGD:1308598 (Rat Genome Database) 298596 (Entrez Gene) Sdhb (Alliance of Genome Resources)	Chr5 q36			P21913 (UniProt | EBI) NM_001100539 (RefSeq)
zebrafish	sdhb	ZDB-GENE-030131-8005 (Zebrafish Model Organism Database) 562149 (Entrez Gene) sdhb (Alliance of Genome Resources)	Chr22			A5PL98 (UniProt | EBI) NM_001098740 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.