Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MPO	HGNC:7218 (HGNC) 4353 (Entrez Gene) 606989 (OMIM) MPO (Alliance of Genome Resources)	Chr17 q22	Chr17:58269855-58280935 (-) GRCh38	acute kidney failure Alzheimer's disease 1 asthma cardiovascular system disease cystic fibrosis end stage renal disease hepatocellular carcinoma keratosis liver cirrhosis lung cancer lung disease lupus nephritis pancreatic cancer vasculitis	P05164 (UniProt | EBI) NM_000250 (RefSeq)
mouse	Mpo	MGI:97137 (MGI) 17523 (Entrez Gene) Gene Tree Mpo (Alliance of Genome Resources)	Chr11 52.22 cM	Chr11:87684610-87695238 (+) GRCm39		17523 (NCBI Gene Model) P11247 (UniProt | EBI) NM_010824 (RefSeq)
rat	Mpo	RGD:1592081 (Rat Genome Database) 303413 (Entrez Gene) Mpo (Alliance of Genome Resources)	Chr10 q26			NP_001388741 (RefSeq) NM_001401812 (RefSeq)
zebrafish	mpx	ZDB-GENE-030131-9460 (Zebrafish Model Organism Database) 337514 (Entrez Gene) mpx (Alliance of Genome Resources)	Chr10			NP_001338766 (RefSeq) NM_212779 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.