Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TPH1	HGNC:12008 (HGNC) 7166 (Entrez Gene) 191060 (OMIM) TPH1 (Alliance of Genome Resources)	Chr11 p15.1	Chr11:18017555-18046269 (-) GRCh38	alcohol use disorder Alzheimer's disease attention deficit hyperactivity disorder borderline personality disorder depressive disorder postpartum depression schizophrenia scoliosis	P17752 (UniProt | EBI) NM_004179 (RefSeq)
mouse	Tph1	MGI:98796 (MGI) 21990 (Entrez Gene) Gene Tree Tph1 (Alliance of Genome Resources)	Chr7 30.43 cM	Chr7:46294065-46321961 (-) GRCm39		21990 (NCBI Gene Model) P17532 (UniProt | EBI) NM_009414 (RefSeq)
rat	Tph1	RGD:3895 (Rat Genome Database) 24848 (Entrez Gene) Tph1 (Alliance of Genome Resources)	Chr1 q22			P09810 (UniProt | EBI) NM_001100634 (RefSeq)
zebrafish	tph1a	ZDB-GENE-030317-1 (Zebrafish Model Organism Database) 352943 (Entrez Gene) tph1a (Alliance of Genome Resources)	Chr25			NP_840091 (RefSeq) NM_178306 (RefSeq)
	tph1b	ZDB-GENE-030805-6 (Zebrafish Model Organism Database) 415103 (Entrez Gene) tph1b (Alliance of Genome Resources)	Chr7			NP_001001843 (RefSeq) NM_001001843 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.