Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ZIC3	HGNC:12874 (HGNC) 7547 (Entrez Gene) 300265 (OMIM) ZIC3 (Alliance of Genome Resources)	ChrX q26.3	ChrX:137566127-137577691 (+) GRCh38	situs inversus visceral heterotaxy X-linked VACTERL association	O60481 (UniProt | EBI) NM_001330661 (RefSeq)
mouse	Zic3	MGI:106676 (MGI) 22773 (Entrez Gene) Gene Tree Zic3 (Alliance of Genome Resources)	ChrX 32.56 cM	ChrX:57075988-57081990 (+) GRCm39	Goldenhar syndrome visceral heterotaxy	22773 (NCBI Gene Model) Q62521 (UniProt | EBI) NM_009575 (RefSeq)
rat	Zic3	RGD:1561261 (Rat Genome Database) 367944 (Entrez Gene) Zic3 (Alliance of Genome Resources)	ChrX q36			NP_001398746 (RefSeq) NM_001411817 (RefSeq)
zebrafish	zic3	ZDB-GENE-030708-2 (Zebrafish Model Organism Database) 368263 (Entrez Gene) zic3 (Alliance of Genome Resources)	Chr14			NP_001001950 (RefSeq) NM_001001950 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.