Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DOCK2	HGNC:2988 (HGNC) 1794 (Entrez Gene) 603122 (OMIM) DOCK2 (Alliance of Genome Resources)	Chr5 q35.1	Chr5:169637268-170083382 (+) GRCh38	immunodeficiency 40	Q92608 (UniProt | EBI) NM_004946 (RefSeq)
mouse	Dock2	MGI:2149010 (MGI) 94176 (Entrez Gene) Gene Tree Dock2 (Alliance of Genome Resources)	Chr11 19.68 cM	Chr11:34176815-34674719 (-) GRCm39		ENSMUSG00000020143 (Ensembl Gene Model) ENSMUSP00000090884 (Ensembl) ENSMUST00000093193 (Ensembl)
rat	Dock2	RGD:1564189 (Rat Genome Database) 360509 (Entrez Gene) Dock2 (Alliance of Genome Resources)	Chr10 q12			NP_001029173 (RefSeq) NM_001034001 (RefSeq)
zebrafish	dock2	ZDB-GENE-031125-1 (Zebrafish Model Organism Database) 571408 (Entrez Gene) dock2 (Alliance of Genome Resources)	Chr14			XP_002664298 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.