Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ICAM1	HGNC:5344 (HGNC) 3383 (Entrez Gene) 147840 (OMIM) ICAM1 (Alliance of Genome Resources)	Chr19 p13.2	Chr19:10271093-10286615 (+) GRCh38	Alzheimer's disease Behcet's disease biliary atresia Crohn's disease diabetic retinopathy Graves' disease Graves ophthalmopathy inflammatory bowel disease iridocyclitis liver cirrhosis malaria multiple myeloma prostate cancer psoriasis skin melanoma type 1 diabetes mellitus	P05362 (UniProt | EBI) NM_000201 (RefSeq)
mouse	Icam1	MGI:96392 (MGI) 15894 (Entrez Gene) Gene Tree Icam1 (Alliance of Genome Resources)	Chr9 7.69 cM	Chr9:20927281-20940113 (+) GRCm39	malaria	ENSMUSG00000037405 (Ensembl Gene Model) ENSMUSP00000083587 (Ensembl) ENSMUST00000086399 (Ensembl)
rat	Icam1	RGD:2857 (Rat Genome Database) 25464 (Entrez Gene) Icam1 (Alliance of Genome Resources)	Chr8 q13			Q00238 (UniProt | EBI) NM_012967 (RefSeq)
zebrafish	icam3	ZDB-GENE-060503-219 (Zebrafish Model Organism Database) 100334824 (Entrez Gene) icam3 (Alliance of Genome Resources)	Chr3			XP_002661307 (RefSeq)
	sc:d0202	ZDB-GENE-080226-9 (Zebrafish Model Organism Database) 569842 (Entrez Gene) sc:d0202 (Alliance of Genome Resources)	Chr3			NP_001091722 (RefSeq) NM_001098252 (RefSeq)
	si:ch73-208g10.1	ZDB-GENE-040108-6 (Zebrafish Model Organism Database) 100002730 (Entrez Gene) si:ch73-208g10.1 (Alliance of Genome Resources)	Chr3			NP_001091731 (RefSeq) NM_001098261 (RefSeq)
	si:ch211-66e2.3	ZDB-GENE-080226-7 (Zebrafish Model Organism Database) 100141487 (Entrez Gene) si:ch211-66e2.3 (Alliance of Genome Resources)	Chr3			NP_001108576 (RefSeq) NM_001115104 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.