Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NOS2	HGNC:7873 (HGNC) 4843 (Entrez Gene) 163730 (OMIM) NOS2 (Alliance of Genome Resources)	Chr17 q11.2	Chr17:27756766-27800529 (-) GRCh38	asthma dementia hypertension Lewy body dementia malaria pulmonary hypertension pulmonary tuberculosis type 2 diabetes mellitus	P35228 (UniProt | EBI) NM_153292 (RefSeq)
mouse	Nos2	MGI:97361 (MGI) 18126 (Entrez Gene) Gene Tree Nos2 (Alliance of Genome Resources)	Chr11 46.74 cM	Chr11:78811613-78851052 (+) GRCm39	type 1 diabetes mellitus	18126 (NCBI Gene Model) P29477 (UniProt | EBI) NM_010927 (RefSeq)
rat	Nos2	RGD:3185 (Rat Genome Database) 24599 (Entrez Gene) Nos2 (Alliance of Genome Resources)	Chr10 q25			Q06518 (UniProt | EBI) NM_012611 (RefSeq)
zebrafish	nos2a	ZDB-GENE-040305-1 (Zebrafish Model Organism Database) 404036 (Entrez Gene) nos2a (Alliance of Genome Resources)	Chr5			NP_001098407 (RefSeq) NM_001104937 (RefSeq)
	nos2b	ZDB-GENE-080916-1 (Zebrafish Model Organism Database) 563654 (Entrez Gene) nos2b (Alliance of Genome Resources)	Chr15			NP_001106973 (RefSeq) NM_001113501 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.