Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GJB4	HGNC:4286 (HGNC) 127534 (Entrez Gene) 605425 (OMIM) GJB4 (Alliance of Genome Resources)	Chr1 p34.3	Chr1:34759740-34762327 (+) GRCh38	erythrokeratodermia variabilis erythrokeratodermia variabilis et progressiva 2	Q9NTQ9 (UniProt | EBI) NM_153212 (RefSeq)
mouse	Gjb4	MGI:95722 (MGI) 14621 (Entrez Gene) Gene Tree Gjb4 (Alliance of Genome Resources)	Chr4 61.51 cM	Chr4:127244879-127247874 (-) GRCm39		ENSMUSG00000046623 (Ensembl Gene Model) ENSMUSP00000101696 (Ensembl) ENSMUST00000106090 (Ensembl)
rat	Gjb4	RGD:621829 (Rat Genome Database) 117055 (Entrez Gene) Gjb4 (Alliance of Genome Resources)	Chr5 q36			P36380 (UniProt | EBI) NM_001389258 (RefSeq)
zebrafish	gjb9a	ZDB-GENE-040406-4 (Zebrafish Model Organism Database) 404728 (Entrez Gene) gjb9a (Alliance of Genome Resources)	Chr17			NP_001007213 (RefSeq) NM_001007212 (RefSeq)
	gjb9b	ZDB-GENE-050616-2 (Zebrafish Model Organism Database) 402821 (Entrez Gene) gjb9b (Alliance of Genome Resources)	Chr19			NP_001007289 (RefSeq) NM_001007288 (RefSeq)
	gjb10	ZDB-GENE-040406-3 (Zebrafish Model Organism Database) 404727 (Entrez Gene) gjb10 (Alliance of Genome Resources)	Chr17			NP_001124108 (RefSeq) NM_001130636 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.