Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AP4B1	HGNC:572 (HGNC) 10717 (Entrez Gene) 607245 (OMIM) AP4B1 (Alliance of Genome Resources)	Chr1 p13.2	Chr1:113894194-113905712 (-) GRCh38	hereditary spastic paraplegia 47	Q9Y6B7 (UniProt | EBI) NM_006594 (RefSeq)
mouse	Ap4b1	MGI:1337130 (MGI) 67489 (Entrez Gene) Gene Tree Ap4b1 (Alliance of Genome Resources)	Chr3 45.52 cM	Chr3:103716836-103729341 (+) GRCm39		ENSMUSG00000032952 (Ensembl Gene Model) ENSMUSP00000044262 (Ensembl) ENSMUST00000047285 (Ensembl)
rat	Ap4b1	RGD:1310529 (Rat Genome Database) 310746 (Entrez Gene) Ap4b1 (Alliance of Genome Resources)	Chr2 q34			NP_001101179 (RefSeq) NM_001107709 (RefSeq)
zebrafish	ap4b1	ZDB-GENE-040426-1284 (Zebrafish Model Organism Database) 393309 (Entrez Gene) ap4b1 (Alliance of Genome Resources)	Chr23			NP_956632 (RefSeq) NM_200338 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.