Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CRB1	HGNC:2343 (HGNC) 23418 (Entrez Gene) 604210 (OMIM) CRB1 (Alliance of Genome Resources)	Chr1 q31.3	Chr1:197201504-197478455 (+) GRCh38	cone-rod dystrophy Leber congenital amaurosis Leber congenital amaurosis 8 pigmented paravenous chorioretinal atrophy retinitis pigmentosa retinitis pigmentosa 12	P82279 (UniProt | EBI) NM_201253 (RefSeq)
mouse	Crb1	MGI:2136343 (MGI) 170788 (Entrez Gene) Gene Tree Crb1 (Alliance of Genome Resources)	Chr1 60.87 cM	Chr1:139124794-139304838 (-) GRCm39	Leber congenital amaurosis 8 retinitis pigmentosa 12	ENSMUSG00000063681 (Ensembl Gene Model) ENSMUSP00000060769 (Ensembl) ENSMUST00000059825 (Ensembl)
rat	Crb1	RGD:1309947 (Rat Genome Database) 304825 (Entrez Gene) Crb1 (Alliance of Genome Resources)	Chr13 q13			NP_001100652 (RefSeq) NM_001107182 (RefSeq)
zebrafish	crb1	ZDB-GENE-050208-382 (Zebrafish Model Organism Database) 560942 (Entrez Gene) crb1 (Alliance of Genome Resources)	Chr22			NP_001038408 (RefSeq) NM_001044943 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.