Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IFT74	HGNC:21424 (HGNC) 80173 (Entrez Gene) 608040 (OMIM) IFT74 (Alliance of Genome Resources)	Chr9 p21.2	Chr9:26947039-27066134 (+) GRCh38	Bardet-Biedl syndrome 22 Joubert syndrome spermatogenic failure 58	Q96LB3 (UniProt | EBI) NM_025103 (RefSeq)
mouse	Ift74	MGI:1914944 (MGI) 67694 (Entrez Gene) Gene Tree Ift74 (Alliance of Genome Resources)	Chr4 43.34 cM	Chr4:94502728-94581466 (+) GRCm39	visceral heterotaxy	ENSMUSG00000028576 (Ensembl Gene Model) ENSMUSP00000030311 (Ensembl) ENSMUST00000030311 (Ensembl)
rat	Ift74	RGD:1359704 (Rat Genome Database) 313365 (Entrez Gene) Ift74 (Alliance of Genome Resources)	Chr5 q33			NP_001007002 (RefSeq) NM_001007001 (RefSeq)
zebrafish	ift74	ZDB-GENE-040718-81 (Zebrafish Model Organism Database) 436658 (Entrez Gene) ift74 (Alliance of Genome Resources)	Chr5			NP_001002385 (RefSeq) NM_001002385 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.