Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SAV1	HGNC:17795 (HGNC) 60485 (Entrez Gene) 607203 (OMIM) SAV1 (Alliance of Genome Resources)	Chr14 q22.1	Chr14:50632058-50668306 (-) GRCh38		Q9H4B6 (UniProt | EBI) NM_021818 (RefSeq)
mouse	Sav1	MGI:1927144 (MGI) 64010 (Entrez Gene) Gene Tree Sav1 (Alliance of Genome Resources)	Chr12 28.94 cM	Chr12:70011786-70033776 (-) GRCm39	colonic disease hepatocellular carcinoma	ENSMUSG00000021067 (Ensembl Gene Model) ENSMUSP00000021467 (Ensembl) ENSMUST00000021467 (Ensembl)
rat	Sav1	RGD:1307253 (Rat Genome Database) 299116 (Entrez Gene) Sav1 (Alliance of Genome Resources)	Chr6 q24			A4V8B4 (UniProt | EBI) NM_001097581 (RefSeq)
zebrafish	sav1	ZDB-GENE-040912-28 (Zebrafish Model Organism Database) 447821 (Entrez Gene) sav1 (Alliance of Genome Resources)	Chr13			NP_001004560 (RefSeq) NM_001004560 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.