Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RYR3	HGNC:10485 (HGNC) 6263 (Entrez Gene) 180903 (OMIM) RYR3 (Alliance of Genome Resources)	Chr15 q13.3-q14	Chr15:33310962-33866121 (+) GRCh38	congenital myopathy 20 hepatocellular carcinoma	Q15413 (UniProt | EBI) NM_001036 (RefSeq)
mouse	Ryr3	MGI:99684 (MGI) 20192 (Entrez Gene) Gene Tree Ryr3 (Alliance of Genome Resources)	Chr2 57.2 cM	Chr2:112461700-113047441 (-) GRCm39		ENSMUSG00000057378 (Ensembl Gene Model) ENSMUSP00000089426 (Ensembl) ENSMUST00000091818 (Ensembl)
rat	Ryr3	RGD:68952 (Rat Genome Database) 170546 (Entrez Gene) Ryr3 (Alliance of Genome Resources)	Chr3 q35			XP_063141024 (RefSeq)
zebrafish	ryr3	ZDB-GENE-041001-165 (Zebrafish Model Organism Database) 561350 (Entrez Gene) ryr3 (Alliance of Genome Resources)	Chr20			XP_009293049 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.