Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ALX4	HGNC:450 (HGNC) 60529 (Entrez Gene) 605420 (OMIM) ALX4 (Alliance of Genome Resources)	Chr11 p11.2	Chr11:44260440-44310139 (-) GRCh38	bronchiolo-alveolar adenocarcinoma colorectal cancer craniosynostosis frontonasal dysplasia 2 hepatocellular carcinoma lung adenocarcinoma lung cancer parietal foramina	Q9H161 (UniProt | EBI) NM_021926 (RefSeq)
mouse	Alx4	MGI:108359 (MGI) 11695 (Entrez Gene) Gene Tree Alx4 (Alliance of Genome Resources)	Chr2 51.62 cM	Chr2:93472779-93511686 (+) GRCm39	parietal foramina	11695 (NCBI Gene Model) O35137 (UniProt | EBI) NM_007442 (RefSeq)
rat	Alx4	RGD:1310201 (Rat Genome Database) 296511 (Entrez Gene) Alx4 (Alliance of Genome Resources)	Chr3 q31			NP_001100023 (RefSeq) NM_001106553 (RefSeq)
zebrafish	alx4a	ZDB-GENE-070712-3 (Zebrafish Model Organism Database) 100006399 (Entrez Gene) alx4a (Alliance of Genome Resources)	Chr7			XP_001340966 (RefSeq)
	alx4b	ZDB-GENE-050208-140 (Zebrafish Model Organism Database) 497424 (Entrez Gene) alx4b (Alliance of Genome Resources)	Chr18			NP_001297007 (RefSeq) NM_001310078 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.