Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HSF4	HGNC:5227 (HGNC) 3299 (Entrez Gene) 602438 (OMIM) HSF4 (Alliance of Genome Resources)	Chr16 q22.1	Chr16:67163761-67169945 (+) GRCh38	cataract cataract 5 multiple types	Q9ULV5 (UniProt | EBI) NM_001040667 (RefSeq)
mouse	Hsf4	MGI:1347058 (MGI) 26386 (Entrez Gene) Gene Tree Hsf4 (Alliance of Genome Resources)	Chr8 53.04 cM	Chr8:105996433-106002477 (+) GRCm39	cataract 5 multiple types	ENSMUSG00000033249 (Ensembl Gene Model) ENSMUSP00000048904 (Ensembl) ENSMUST00000036127 (Ensembl)
rat	Hsf4	RGD:1310808 (Rat Genome Database) 291960 (Entrez Gene) Hsf4 (Alliance of Genome Resources)	Chr19 q11			NP_001099647 (RefSeq) NM_001106177 (RefSeq)
zebrafish	hsf4	ZDB-GENE-050306-18 (Zebrafish Model Organism Database) 503739 (Entrez Gene) hsf4 (Alliance of Genome Resources)	Chr18			Q5CZP2 (UniProt | EBI) NM_001328208 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.