Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EIF2AK3	HGNC:3255 (HGNC) 9451 (Entrez Gene) 604032 (OMIM) EIF2AK3 (Alliance of Genome Resources)	Chr2 p11.2	Chr2:88556741-88691518 (-) GRCh38	type 1 diabetes mellitus Wolcott-Rallison syndrome	Q9NZJ5 (UniProt | EBI) NM_001313915 (RefSeq)
mouse	Eif2ak3	MGI:1341830 (MGI) 13666 (Entrez Gene) Gene Tree Eif2ak3 (Alliance of Genome Resources)	Chr6 32.09 cM	Chr6:70821499-70882229 (+) GRCm39	Wolcott-Rallison syndrome	ENSMUSG00000031668 (Ensembl Gene Model) ENSMUSP00000034093 (Ensembl) ENSMUST00000034093 (Ensembl)
rat	Eif2ak3	RGD:70884 (Rat Genome Database) 29702 (Entrez Gene) Eif2ak3 (Alliance of Genome Resources)	Chr4 q32			Q9Z1Z1 (UniProt | EBI) NM_031599 (RefSeq)
zebrafish	eif2ak3	ZDB-GENE-050414-2 (Zebrafish Model Organism Database) 559564 (Entrez Gene) eif2ak3 (Alliance of Genome Resources)	Chr13			XP_021336441 (RefSeq) NM_001077149 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.